A great alternative to Tkinter that wraps wxWidgets with SWIG.
Main wxPython Website
wxPython Wiki
wxPython Cookbook
wxPython Mailing List
http://www.manning.com/rappin/
A Look at wxPython
Choosing wxPython over Tkinter
Graphical Toolkits for OS X: wxPython
Python Programming on Win32 using WxPython
